Information about silicones - what are they used for in cosmetics, are they useful or harmful?

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Silicones in cosmetics – what they are, what they are used for. Here is a list of the names of the most harmful.

Silicones are a common ingredient in skin and hair care products. They are still the subject of controversy.

Consumers are now strongly advised to use silicone products in cosmetics with caution. The reason is their ability to have a negative effect on the dermis.

The ingredient eliminates imperfections and improves appearance. But consumers need to be aware that it is prone to cause negative effects.

The specialty of silicone products, from implants to phone cases, is that they are smooth and flexible. We want the skin to feel this way. This rubber-like material has found use in cosmetics and is kindly accepted in beauty salons as an ingredient safe for the epidermis.

Currently, requests for face and hair cosmetics without silicones and parabens have increased. Let's figure out what is the benefit and whether there is harm from using these components.

• 1 What is
• 2 How are they indicated in the composition?
• 3 Application in skin and hair care
• 4 Types
• 5 Benefit
• 6 Harm

“Silicon issue. For or Against"

Pharmacists and cosmetics manufacturing companies, supporters of natural creams and synthetic formulations are engaged in serious debate about the benefits and harms of dimethicone and other products containing silicone oils. Moreover, these discussions have been going on since the mid-60s of the last century.

In 2008, environmentalists joined the debate. They tried to prove that silicones accumulate in the aquatic environment and threaten water-dwelling organisms. They couldn't provide evidence, but they made some noise. The US Food and Drug Administration ( FDA has officially approved the use of Dimethicone in cosmetics .

Large cosmetic brands have conducted their own tests, which have proven that dimethicone in cosmetics does not cause allergies, irritation, or intoxication on the skin.

Details

Types of silicones

Water-soluble silicones (end with –onol) are easy to wash off and are ideal for cosmetics. Most often present in shampoos and conditioners.

Water-insoluble silicones are more often found in decorative cosmetics: after their use, a protective film is formed on the skin that does not allow harmful substances and contaminants to pass through. Thanks to this type of silicone, makeup becomes durable. However, the accumulation of this substance in the body has an adverse effect on the skin.

Volatile silicones – have a small molecular weight. Safe. They can be found in thermal protection for hair.

polymer silicones have a high molecular weight. They have a cumulative effect. Often they solve the problem only externally (for example, split ends).

Properties of silicones

• Compatible with water and other cosmetic ingredients.
• Gives the skin a feeling of softness, silkiness, velvety, eliminates the feeling of stickiness.
• They form a film on the skin that protects against ultraviolet rays and hard water.
• Protects skin from chapping.
• Softens the skin, retaining moisture.
• Ensure uniform distribution of the cosmetic product on the skin, lips, eyelashes.
• Regulates the formation of foam in shower gel and shaving products.
• Included in ointments for wound healing.
• Blood transfusion systems and drainage tubes are made from silicones.

The benefits and harms of silicones

Silicones in cosmetics, to the surprise of many, have a lot of advantages :

Texture.

Silicones make the texture of cosmetic products comfortable for applying to the skin.

Coating.

For example, a primer, due to the presence of silicones in its composition, fills in uneven skin. This way you can hide imperfections, the skin will look perfect, and its quality will visually improve.

Protection.

Products with silicones form a protective film on the surface of the skin, preventing pollution and harmful substances (free radicals) from penetrating into it. Silicones also retain moisture in the skin. Manufacturers often present this property on cosmetic labels as a deep moisturizing effect. But this is not true: silicones simply do not allow moisture to evaporate, but do not moisturize the skin.

Persistence.

Silicones in decorative cosmetics provide longevity to makeup.

Sometimes the above advantages turn into disadvantages - the negative attitude towards silicones of many people is due to them.

Temporary effect.

After applying a cream containing silicones, you will notice that wrinkles have become less visible and pores have become smoother. But this is an external effect that lasts only for the time when the product is applied to the skin. By removing makeup, we return the skin to its original state. That is, cosmetics containing silicones do not affect the functionality of the skin and the functioning of its cells.

Impenetrability.

While preventing harmful substances from entering the skin, silicones in cosmetics also prevent the entry of beneficial ones. The silicone layer fills the pores on the skin, preventing it from “breathing” fully. Under such an impermeable layer, favorable conditions arise for the formation and reproduction of bacteria. As a result, the skin becomes inflamed. Approximately the same situation occurs when hair is exposed to silicones.

Difficult to remove.

Silicones are not easy to wash off from skin and hair. Often, unwashed, they remain on the skin and hair and accumulate, preventing the full renewal of these organs. The dense silicone layer on the skin can be washed off using intensive cleansers and makeup removers.

NOTE: In optimal quantities, silicones allow the skin to “breathe”. If their quantity is exceeded, the pores and hair follicles become clogged.

As a rule, the proportion of silicones in facial cosmetics does not exceed 8%. The permissible concentration of silicones in hair cosmetics is up to 20%. In this way, possible harm is minimized.

Decorative cosmetics containing silicones

Primer.

Silicone is necessary in the primer so that the relief on the skin can be evened out. It is thanks to the silicones that fill wrinkles and pores on the skin that a Photoshop effect is created after using the primer. Makeup applied over a primer base lasts longer.

Concealer.

The silicones in its composition make the coating on the skin silky, soft and pleasant to the touch.

Pomade.

The addition of silicones to the lipstick ensures easy application on the lips, a smooth shade, and uniform color distribution.

Mascara.

Thanks to silicone, eyelashes become more voluminous and protected from external influences. The silicone-containing mascara adheres tightly to the eyelashes. It is important to remove makeup correctly if you use this mascara.

Other cosmetics that may contain silicone

In skin care cosmetics these are butters, body milk, tonics. In hair care products these are shampoos, sprays, serums, balms. Silicone is also added to bubble baths and sunscreens.

How are silicones designated?

The most common silicone in cosmetics is dimethicone. other substances ending in –cone are also silicones. Examples: methicone, cyclomethicone, trimethicone. The list of substances ending in –onol also includes silicones (dimethiconol).

Indicates silicones in the composition and the ending –siloxane (example – cyclopentasiloxane). It’s difficult to remember the names of silicones, but it’s better to keep a couple of the most common ones in mind.

The most popular silicone, dimethicone, is mainly used in facial skin care products; other silicones can be found in hair cosmetics.

Disadvantages of silicones in cosmetics:

Comedogenicity. The film on the skin and hair formed due to the silicone layer prevents the skin from cleansing.

Carcinogenicity. There is an opinion that silicones are carcinogenic substances. But a study by Danish scientist S. Friis proved that silicone in implants has no effect on the development of breast cancer.

Allergies. Silicones themselves are not toxic, but the silicone film provokes the growth of bacteria and causes inflammation. If there is an allergy to some component in a cosmetic product, then the silicone film intensifies the allergic reaction.

How is silicone designated and what is its nature of origin?

The names end with methicone or siloxane. For example, these are polydimethylsiloxane, dimethicone, cyclomethicone, dimethicone alkyl-acrylat cross-polymer and so on. The difference in names is due to the peculiarities of the arrangement of atoms, in the three-dimensional structure of molecules, etc. These are fully synthesized substances, including atoms of oxygen, carbon, hydrogen, and silicon. If the composition contains methyl groups, such substances are called dimethicones, and if there are rings in the structure, cyclomethicones are formed.

We asked IMAGE Skincare to join in on this discussion and here's the response we received from Ashleigh Kehrt, the brand's international educator. She suggests reviewing and dismantling the most common myths associated with silicones.

Silicones in cosmetics

Why did silicone, seemingly completely unrelated to the sphere of beauty, begin to be used in cosmetics? Silicones are used in face and body cosmetics to ensure that textures stay on the skin as long as possible. Silicone in cosmetics can form a film, filling wrinkles and hiding imperfections. And thereby visually making the face younger, healthier, and the tone more even. This polymer also has a water-repellent effect, so it is actively added to long-lasting cosmetics: mascaras, foundations, makeup bases. And, as you know, long-lasting cosmetics are not so easy to wash off; thanks to silicone, it seems to eat into your face. It is very difficult to wash off such war paint; it requires considerable effort and special products, which often injure the skin, causing an aggressive effect on it.

What does such a seemingly universal product consist of?

Silicone is a chemically created substance that contains atoms of oxygen, silicon, hydrogen and carbon.

As you can see, there is nothing natural or related to nature in its composition. Exclusively chemical method of creation. It may contain various additives that slightly change the properties and form different types of silicone. Almost every day, chemists invent new modifications of silicone, encrypting them in the composition of cosmetics in such a way that it is difficult to find even with a magnifying glass. The name of silicones in cosmetics in the list of ingredients can be recognized by words ending in -methicone (methicone), -silicone (silicone), -siloxane (siloxane). Below we will look at some of them, the most common in the cosmetics industry.

Why do silicones have such a bad reputation?

Mainly because of alarmism.

What is alarmism? The tendency to experience terrible, unaccountable, uncontrollable fear in the face of real or imaginary danger and the desire to avoid it by any means, simultaneously spreading panic around. This fear quickly spreads through social media, exaggerating the danger, and leading to a proliferation of, to put it mildly, inaccurate information.

That's what makes this whole "problem" so overwhelming. It all started with complaints on online forums about silicones weighing down long hair. This problem has been associated with the overuse of 2-in-1 shampoos, which contain very high molecular weight silicone gums combined with cationic polymers to improve application of these substances. Then it somehow snowballed and all silicones became dramatically harmful, although in fact this is far from the case.

Today, in a world of ingredient transparency and high levels of education, standards have been set for consumer expectations in cosmetic products. All parties involved—marketers, manufacturers, retailers, and decision makers—have a responsibility to jointly develop on-pack ingredient transparency along with quality consumer education to properly inform cosmetics users about which ingredients are safe and unsafe, based on real-world evidence and clinical research.

Hand skin protection

Film-forming components are indispensable for protecting hands from any adverse factors, from working with soil to alcohol antiseptics. The function of the cream here is also a barrier, unlike organic oils, for example. Silicones cannot restore skin or eliminate deep dryness.

And these products can: Your hands won’t show your age: 6 effective products that will make your skin soft.

Are silicones good for sensitive skin?

Absolutely!

Silicones are some of the most harmless and gentle ingredients known to men and women, as evidenced by nearly 70 years of research and history of their use.

Due to the incredibly low incidence of allergies, hospitals use silicone-based dressings for wound care. In the consumer market, over-the-counter skin protectants and silicone scar sheets are FDA approved for scar prevention. These are inert, non-reactive ingredients proven to be safe for the skin.

It is commonly believed that natural means safe, and yet, ironically, essential oils are a typical example of natural ingredients that contain allergens. However, most consumers are still unaware that natural ingredients can cause serious skin reactions.

General information

Silicones are a group of polymers. Many of them are biologically compatible with the tissues of the human body - this is the reason for their use in cosmetology and medicine. Silicone is made from quartz and methanol. The substances are colorless, odorless and tasteless, resistant to temperature changes, do not oxidize or deform, and are used mainly in liquid form, which makes them very valuable in production. They are used in the manufacture of dentures and the preparation of ointments. In plastic surgery, silicone implants are used (nowadays, however, this is no longer such a popular method of breast enlargement).

In cosmetics, these substances are used for the reason that they can have a softening effect: cosmetics adhere better to the skin, distribute evenly over it, and have a texture that is pleasant to the touch. In hair products, silicones smooth out the scales on the hair, making it smoother and increasing volume.

FOR REFERENCE: From a chemical point of view, silicones are atoms of silicon and oxygen connected to each other, to which other organic groups are attached.

Are silicones comedogenic and do they cause acne?

No!

Claims that silicones in any form cause or worsen skin problems have not been substantiated by any published research, nor have there been any reports of silicones causing sensitization or in any way “worsening” skin conditions.

In fact, the opposite is true, which makes misinformation difficult to understand. Almost all claims that silicones are harmful to the skin are myths or based on anecdotal evidence.

Silicones are permeable materials, which means they allow the skin to breathe. And further. Silicone elastomers, due to their three-dimensional network, are particularly used in acne medications because they help absorb sebum. It is for this reason that many primers are based on silicone elastomers. Since silicones do not oxidize on the skin, they do not form breakdown products that could cause irritation, clog pores or cause acne. They do not support the growth of microorganisms, do not integrate into the lipid structures of the stratum corneum and do not disrupt the barrier function.

The American Academy of Dermatology recommends silicone-based cosmetics for patients with cystic acne or rosacea. Moreover, silicones help relieve the unpleasant side effects of medications used to treat acne - in particular, benzoyl peroxide and antibiotics. In addition, it has been experimentally proven that silicones do not change the microstructure of the lipid layers of the skin and, accordingly, cannot cause disruption of the barrier function.

We are looking for a useful replacement for silicones

In nature, analogues of chemically created silicone in cosmetics are natural wax, keratin and silk proteins - look for these ingredients in the composition. If you want real, healthy and high-quality hydration, aloe vera, shea butter, and jojoba can help you. If you want to look younger and fresher, choose cosmetics with hyaluronic acid, collagen, and ferulic acid. These ingredients will really help smooth out fine wrinkles, nourish the epidermis with useful substances, and increase its elasticity.

In conclusion, all of the above suggests one important conclusion - there is no benefit from silicone. It gives only temporary and short-lived effects, does not heal anything and does not restore anything. Health Canada has generally recognized silicones as harmful, and some of them even toxic. BUT, according to the scientific community, this polymer is found in 75% of all cosmetics. Silicones are prohibited for use by eco-standards for organic cosmetics. Therefore, the most important and most important thing is to ALWAYS read the ingredients of the product you want to buy. It’s better to use certified cosmetics. And if your life credo is to be, not to appear (beautiful, well-groomed, young), then you are definitely not on the right track with silicones.

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Are silicones stable and degradable in the environment?

Simply put, yes.

Silicones are derived from quartz (also known as sand), the second most abundant mineral on Earth. In the environment, silicones quickly evaporate and decompose in the air when exposed to sunlight. Small amounts that end up in water are not liked because they are so insoluble, and complete the cycle by being distributed into the soil, where they decompose, turning back into sand. All this has been proven a long time ago, and contrary to some of the alarmism we talked about earlier, silicones do not accumulate in the environment.

Wow effect

If you need a one-time and significant upgrade of your appearance, for example, before an important event, you cannot do without the help of silicones. Their film-forming components visually smooth the skin, compensate for fine wrinkles and unevenness, and give unrealistic smoothness and shine to the hair. For systemic care, this does not make much sense, since there are no real changes in the skin; the proposed option is good just “for the exit”.

They are not absorbed into the skin and stop their action immediately after washing off.

Yes.

A misconception we've heard is that silicones dry out the skin.

Silicones are one of the very few active ingredients used in creams for wounds, scars and even burns to form a protective barrier that prevents transepidermal water loss, speeds up healing and does not support the growth of microorganisms. This is such an important use for silicones that people, including children, who suffer life-threatening skin injuries, including burns, are treated in the hospital with silicone sheets. Then with silicone based treatments because they reduce the chance of infection, retain moisture and never irritate the skin. Also, not a single study has confirmed the allergenicity of silicones.

pros

Smoothes the skin

Silicones soften the skin and make it smoother. As part of primers, they even out the surface of the skin, give it a healthy glow and leave a pleasant feeling.

Protect from external influences

Silicones create a kind of film on the surface; hair products often say that they “seal” the hair, making it smooth. This barrier prevents external pollutants from penetrating the skin.

The likelihood of getting an allergy is no greater than from other components

Those who say that cosmetics with silicones can cause an allergic reaction are right, but this can be said about any cosmetic components. Brands and influencers promoting natural self-care and “clean beauty” often equate the words “organic” with “safe.” It is important to understand that natural ingredients can also be allergens, and the likelihood of this is even higher than in the case of artificial ingredients.

Read on topic: 6 ingredients in cosmetics that people with sensitive skin should avoid

Are there other ingredients, such as silicone, that don't deserve a bad rap?

The Internet is full of alarmists. Toxicology is essentially a completely misunderstood field, the topic can take hours to cover and is easily misrepresented. The best example is hydrogen oxide gas. It's deadly if someone inhales it for too long, but it's used in most cosmetics and no one wants to ban it. We're talking about... water! See how easy it is to mislead people with scientific terms that become scary if misunderstood.

Exceptional durability

Cosmetics with silicones (due to the properties of the same film) allow you to fix makeup so that it survives rain, heat, unfavorable conditions of the metropolis, and even a medical mask. If you have a photo shoot in extreme conditions or work in full dress all day, trust the silicone makeup base. It will not only withstand the test, but also protect the skin from dust and dirt.

But wash your face thoroughly afterwards. The Korean cleansing system will help you best here: Simple and affordable: Korean care for the lazy and always busy.

Are silicones safe?

The Clean Beauty movement, a beauty trend whose main principle is the safety of ingredients, and not their origin (plant or synthetic), does not play a leading role when it comes to drug compositions. The concept of “Clean Beauty” means that cosmetics do not contain substances that are toxic or harmful to the skin, and were created in safe laboratory conditions with full respect for the environment and animals - the products are not tested on conditional rabbits and are bottled in biodegradable packaging.

In fact, what's safer for your skin than an inert, non-reactive ingredient that enhances the aesthetics of formulas while delivering incredible sensory aspects without irritating your skin? Case in point: silicones. Since they are not animal derived, they are vegan by default and made with love.

Finally, silicones are non-GMO, colorless, odorless and non-ionic, with no oxidation problems. The new Clean Beauty movement must understand and prioritize safety and effectiveness, not just the origin of ingredients.

I would like to add to Ashley’s words the fact that SCCS and CIR experts have repeatedly analyzed the safety data for silicones, and it has never been confirmed that silicones can cause irritation to the eyes, skin or lungs. On the contrary, the absence of irritating and sensitizing effects has been experimentally proven.

Over the long history of the use of silicones, a fairly large amount of data has been collected, and it is constantly being updated. For example, there is the Siloxane Research Program; In the USA, there is a Center for the Study of the Impact of Silicones on the Environment, Health and Safety (Silicones Environmental, Health, and Safety Center), which regularly publishes research results. The safety data is constantly analyzed by the CIR expert panel and the SCCS expert council of the European Commission. According to their conclusions, supported by dozens of carefully conducted studies, silicones are recognized as non-toxic and non-carcinogenic, they do not cause sensitization and genetic disorders, do not accumulate in the body, and even with industrial use do not pose a danger to workers either in terms of acute reactions or the risk of occupational diseases.

How are things in Russia?

Manufacturers of domestic cosmetics are guided by the document “On the safety of perfumery and cosmetic products”, technical regulations of the Customs Union TR CU 009/2011. It defines ingredients that are prohibited/allowed for use in cosmetics, their concentrations and information that should be indicated about them on the packaging. Interestingly, in Russia silicones are allowed in any form.

Always look at the ENTIRE formula of the drug , where exactly dimethicone is, whether the active ingredients are encapsulated in the drug or not, the composition consists of 5 or 35 ingredients, and so on. All this is very important when choosing one drug or another.

IMAGE Skincare is a professional cosmeceutical that, above all, puts the safety and effectiveness of its products first. That is why do not self-prescribe, but to select medications, contact certified cosmetologists.

Types of silicones

There are quite a few varieties of these substances, but the main ones are dimethicone and cyclopentasiloxane. They have different properties and applications in hygiene products and decorative cosmetics.

Dimethicone

It consists of large, heavy molecules and coats the hair shafts well. On the other hand, it is poorly washed off, weighs down the hair, and settles on the surface of the skin.

Dimethicones have different viscosities depending on the length of the molecule. The main representative of this series is hexamethyldisixolane, which is a liquid. It is often used in antiperspirants and deodorants, as well as products applied to damp hair. High molecular weight, slightly volatile compounds are often used in water-repellent creams in combination with mineral oils

Cyclopentasiloxane (Cyclomethicone)

Volatile silicones with small molecular sizes dissolve well in water and do not accumulate on the surface of the epidermis.

Cosmetic products often contain both of these components. Their various combinations make it possible to create compositions with specified properties. Silicone molecules create a matrix mesh on the surface of the skin or hair that retains the beneficial substances added to the cosmetic product for a long time. When replacing silicone with glycerin or vegetable oils, there is a high probability of clogging pores and the formation of comedones.

Cyclomethicones containing ring-shaped structures are used in hair end treatments, pomades, aerosols and sprays.

Alkyldimethicones

Used less frequently. These are wax-like substances that are part of skin care and sunscreen creams, decorative cosmetics, such as lipsticks, mascara.

Phenylmethicone

Enhances hair shine, forms a slip film and makes hair smooth.

Dimethicone copolyol

A complex molecule with surfactant properties, which is why it is used in bath foams, liquid soaps and shower gels.

Cosmetics based on dimethicone

In addition to hair care products and moisturizing creams, dimethicone is added to almost all products in cosmetics. For example, eye shadows and lipsticks with silicone oils are smooth in texture, easy to apply, have a bright, rich color, and last a long time. It is believed that these substances are quite safe and do not react with the skin.

Body deodorants and tanning products

Dimethicone in their composition often sets the tone and adds the following qualities:

• reduces the allergenicity of synthetic components in the product;
• helps distribute the product evenly throughout the body;
• prevents the appearance of whitish stains on skin and clothes;
• makes the products waterproof. You bathe, and the products continue to work!

Lipstick

Everything here is quite contradictory. Silicone additives, on the one hand, increase the shelf life of lipstick, on the other hand, they form a film that prevents the absorption of beneficial substances. The film, in turn, retains moisture inside, which means the lips do not dry out. In addition, dimethicone contains:

• provides lips with a uniform, “varnished” surface,
• enhances shine and creates the effect of moist lips.

Tip: How to find out the composition of lipstick? Usually the components are listed on boxes, which are immediately thrown into the trash. Therefore, for information, contact the official websites of manufacturing companies or the catalogs of large online cosmetics stores. The composition of the lipstick must be specified in the characteristics.

Mascara

Silicone components improve the consumer properties of the product:

• create a shimmering effect,
• contribute to the uniform distribution of pigment across the eyelashes,
• makes mascara waterproof.

Foundations

When a foundation with silicone is applied to the skin, a thin elastic film is formed that protects against contamination. In addition, the film again performs a protective function and retains moisture in the skin. The cream spreads in a thin, even layer over the surface of the skin and fills the pores well. The skin looks smooth and silky, there is no greasy shine. Wrinkles are visually smoothed, pores are narrowed.

Warning: if you use foundation with silicone components, be sure to wash off the product in a timely manner and then wipe your skin with toner.

At least once a week, for example, on Sunday, give your skin a day off.

Nourishing skin creams

Dimethicone is added to creams as a thickener; it also makes the texture less greasy and sticky, pleasant to the touch. What's also great is the added UV protection.

Main features and uses of phenyl trimethicone

In terms of its optical properties (refractive index of sunlight), this substance is close to the properties of hair. This allows phenyl trimethicone, when applied to hair, to instantly make it shiny, giving it a glossy and well-groomed appearance, and the shine will be more intense than when using other silicone components. Due to this property, this ingredient is widely used in shine sprays, hair sprays and hair care products. In addition, phenyl trimethicone improves hair texture and makes it silky to the touch (this effect is especially noticeable on damaged hair).

This component additionally provides thermal protective properties to hair cosmetic products.

Phenyl trimethicone is an excellent conditioning additive not only for hair, but also for skin. It combines well with a variety of oils and can reduce product stickiness and stickiness in moisturizers and sunscreens. As part of cosmetics, it is easily distributed over the skin and hair and forms a non-greasy and non-sticky film, which prevents the loss of moisture from the surface and gives a moisturizing effect. Therefore, it can be found in skin creams and lotions, shampoos and hair conditioners (including leave-in conditioners and heat protectants for hair).

Phenyl Trimethicone in Estel Curex Therapy 2-phase spray

It is worth noting separately that the phenyl trimethicone film does not allow moisture to pass through from hair and skin, or vice versa. This ensures the water-resistant effect of certain medications, such as sunscreens for hair and skin. It combines well with UV filters (even dissolves them) and increases the sun protection properties of drugs (SPF). In addition, such a film is permeable to gases, so the skin under such a film breathes.

Phenyl Trimethicone can often be found in wax-, oil- and alcohol-based antiperspirants, where it prevents the formation of white spots.

Phenyl trimethicone is not soluble in water, but is completely washed out by shampoos containing Lauryl Sulfate, Laureth Sulfate or Cocamidopropil Betaine.

Component Security

The safety of phenyl trimethicone was assessed by the Cosmetic Ingredient Review (CIR) panel of experts. A panel of CIR experts based on scientific evidence concluded that the component is safe for use in cosmetics and personal care products. It does not manifest itself as a toxic substance or irritant, and in laboratory studies it did not cause mutations. Moreover, its use did not harm laboratory animals even in relatively higher concentrations than those used in cosmetics and personal care products.

Composition of Neutrogena revitalizing lip balm.jpg

The above properties are due to the large size of phenyl trimethicone molecules, which prevents their absorption by the skin. And if a substance cannot penetrate the skin, it cannot trigger a response from immune system cells. And, as a result, they do not cause irritation or allergies. In addition, there is not even a cumulative effect, since for its manifestation it is necessary that the substance penetrates the skin cells.